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 Shande Chen
Shande Chen    PhD
Professor - Biostatistics & Epidemiology
 
Contact address      
Department  Biostatistics and Epidemiology
Email  Shande.Chen@unthsc.edu  
Fax No:  817-735-2314  
   
 
Professional Preparation
Doctor of Philosophy,  Statistics,  University Of Rochester,  NY
Master of Arts,  Statistics,  University Of Rochester,  NY
Bachelor of Science,  Applied Mathematics,  Shanghai Univ.Science & Techno,  
 
Appointments   More...    Close... 
2014 - Current    Member    Institutional Review Board (IRB)
2012 - Current    Member    SPH Biostatistics - Search Committee (Associate/Full Professor)
2009 - Current    Professor    UNTHSC
Current    Member    SPH Biostatics Meeting
Current    Member    SPH Faculty Meeting
2015    Member    SPH Promotion & Tenure Committee
2012 - 2014    Member    Faculty Grievance and Appeal Committee
2014    Member    Communications Team
2014    Member    SPH Research Committee
2011    Member    SPH Doctoral PhD Committee
2001 - 2009    Associate Professor    UNTHSC
        
    Member    SPH MPH Practice Committee
 
Teaching   More...    Close... 
BIOS 6391  Advanced Topics in Biostats  Fall 2013
BIOS 5735  Analysis of Variance  Spring 2005 - Spring 2008
BIOS 5320  Analysis of Variance  Spring 2010 - Spring 2014
BIOS 5210  Biostatistics for PH I  Summer 2007
BIOS 6318  Clin Trials & Survival Analy  Spring 2010 - Spring 2014
BIOS 6775  Clin Trials&Survival Analysis  Spring 2005 - Spring 2009
BIOS 6399  Doc Ind Study in Biostats  Spring 2014
BIOS 6910  Doc Ind Study in Biostats  Summer 2004 - Summer 2008
BIOS 6395  Doctoral Dissertation  Fall 2009 - Spring 2014
BIOS 5910  Independent Study in Biostats  Spring 2005 - Summer 2009
BIOS 5399  Independent Study in Biostats  Summer 2010 - Fall 2012
BIOS 5314  Intro to Statistical Packages  Fall 2009
BIOS 6311  Linear Models  Fall 2014
BIOS 6326  Methods of Clinical Trials  Fall 2015 - Spring 2017
BIOS 6312  Methods of Survey Sampling  Spring 2013 - Spring 2016
BIOS 5300  Principles of Biostatistics  Summer 2015 - Fall 2017
BIOS 6310  Probability & Stat Inference  Fall 2016
BIOS 5312  Regression Analysis  Fall 2009 - Fall 2013
BIOS 5730  Regression Analysis  Fall 2004 - Fall 2008
BIOS 5311  Regression and ANOVA  Fall 2014 - Spring 2016
BIOS 5395  Thesis  Fall 2013
BMSC 5200  Biostatistics for Biomed Sci  Summer 2006 - Summer 2007
BMSC 5400  Biostatistics for Biomed Sci  Summer 2012
CLIN 9290  Clinical Medicine 2 + Ethics  2007
SPH 6900  Doctoral Capstone  Spring 2009
SPH 6860  Public Health Practice Res  Spring 2009
SPH 5950  Thesis  Spring 2006 - Fall 2007
 
Student Advising   More...    Close... 
Song,Bing  -  2017-06-06
Dissertation Committee, GSBS Molecular Genetics, PhD in Biomedical Sciences    UNT Health Science Center
Yang,Mei  -  2014-10-13
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Chu,Tzu Chun  -  2014-10-13
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Gupta,Apeksha Ajay Kumar  -  2014-10-13
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Panchal,Hardik  -  2014-01-09
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Olanipekun,Olalekan A  -  2013-09-11
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Ilouga,Nnamdi Ezechukwu  -  2013-09-11
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Anne,Sruthi  -  2013-01-14
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Zhang,Qianzi  -  2013-01-07
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Raza,Adil  -  2012-08-30
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Roy,Anindita ManojKumar  -  2012-08-30
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Mamawala,Mufaddal  -  2012-08-30
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Ghanta,Goutham  -  2012-08-30
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Thakore,Sanket R  -  2012-08-21
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Mangla,Kapil  -  2012-06-14
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Patel,Pinal Shaileshbhai  -  2012-06-14
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Kadiani,Adnan  -  2012-06-14
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Oza,Nidhish V  -  2010-08-22
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Baidhya,Sweety  -  2010-08-22
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Shah,Rikin Kartikbhai  -  2010-08-16
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Okpalaji,Chukwujekwu I  -  2010-01-10
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Yuan,Chengbo  -  2009-08-23
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Student Name Withheld  -  2009-05-25
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Patel,Nita  -  2009-05-18
Dissertation Committee, SPH Biostatistics, Doctor of Public Health    UNT Health Science Center
Trivedi,Chintan  -  2009-01-12
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Student Name Withheld  -  2008-11-23
Dissertation Committee, SPH Clinical Research, Doctor of Public Health    UNT Health Science Center
Wang,Xiaofeng  -  2008-08-25
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Nawaz,Muhammad Kashif  -  2008-08-04
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Zahn,Mandy Michelle  -  2008-05-27
Thesis Committee, SPH Clinical Research, Master of Public Health    UNT Health Science Center
Student Name Withheld  -  2008-05-09
Advisor, SPH Clinical Research, Master of Public Health    UNT Health Science Center
Student Name Withheld  -  2008-01-25
Advisor, SPH Biostatistics, Doctor of Public Health    UNT Health Science Center
Venegas-Rios,Heidi Liam  -  2008-01-07
Dissertation Committee, SPH Biostatistics, Doctor of Public Health    UNT Health Science Center
Student Name Withheld  -  2007-09-07
Advisor, SPH Clinical Research, Master of Public Health    UNT Health Science Center
Lemp,Jessie Marie  -  2007-09-01
Advisor, SPH Biostatistics, Doctor of Public Health    UNT Health Science Center
Lemp,Jessie Marie  -  2007-09-01
Major Professor, SPH Biostatistics, Doctor of Public Health    UNT Health Science Center
Sanghvi,Chirag  -  2007-08-02
Major Professor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Maresh,Kyong Oak  -  2007-06-02
Advisor, SPH Biostatistics, Doctor of Public Health    UNT Health Science Center
Maresh,Kyong Oak  -  2007-06-02
Major Professor, SPH Biostatistics, Doctor of Public Health    UNT Health Science Center
Newball,Sally E  -  2007-01-22
Advisor, SPH Clinical Research, Master of Public Health    UNT Health Science Center
Shah,Pankhil Virenkumar  -  2007-01-19
Advisor, SPH Clinical Research, Master of Public Health    UNT Health Science Center
Shah,Siddharth Ashokkumar  -  2006-08-24
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Student Name Withheld  -  2006-06-26
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Lu,Yan  -  2006-06-20
Advisor, SPH Clinical Research, Master of Public Health    UNT Health Science Center
Sreekantan,Mithun  -  2006-02-14
Thesis Committee, SPH Environmental Health, Master of Public Health    UNT Health Science Center
Higgins,NaKedra RaShard  -  2006-01-26
Advisor, SPH Clinical Research, Master of Public Health    UNT Health Science Center
Stevens,Michael Alan  -  2006-01-26
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Monroe,Cheryl D.  -  2006-01-13
Prof Report Committee Member, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Bradshaw,Ledjona D.  -  2005-08-26
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Davis,Shavsha  -  2005-06-02
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Wu,Gang  -  2005-02-22
Thesis Committee, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Spock,Shannon D.  -  2005-02-22
Advisor, SPH Clinical Research, Master of Public Health    UNT Health Science Center
Barrett,Jeffrey Leland  -  2005-02-18
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
Chen,Yue  -  2004-09-28
Advisor, SPH Biostatistics, Doctor of Public Health    UNT Health Science Center
Lonappan,Margaret  -  2004-09-28
Advisor, SPH Biostatistics, Master of Public Health    UNT Health Science Center
 
Research and Expertise
 RESEARCH INTERESTS 
 Statistical methodology 
 
Grants and Contracts   More...    Close... 
2017 Project RN0084: Novel Mechanistic Targets of Steroid Hormones in the Brain - Core A (2 P01 AG027956-05A1)
CTR FOR NEUROSCIENCE DISCOVERYNIA: National Institute on Aging
2016 Project RN0142: Variability of Triaxial Plantar Loading in Diabetic Patients (R15DK104257)
PHYSICAL THERAPYNIDDK: Diabetes & Digestive & Kidney
2016 Project RF00015: Health Disparities in Alzheimer's Disease among Mexican Americans (1R56AG054073-01)
CTR FOR ALZ & NEURO DIS RSRCHNIA: National Institute on Aging
2016 Project RF00014: HIV-1 Infection and Latency in Astrocytes (R01 DA043162)
CELL BIOLOGY & IMMUNOLOGYNIDA: National Institute on Drug Abuse
2016 Project RN0130: Biphosphonate Use and Lung Cancer Incidence and Mortality in Elderly Women (RO3CA184327)
BIOSTATISTICS & EPIDEMIOLOGYNCI: National Cancer Institute
2015 Project RF0087: Assessing User Barriers of PAPRs in Healthcare Work Settings (200-2015-M-63768)
ENVIRONMENTAL & OCCP HLTHCenters for Disease Control
2015 Project RN0138: miR-132, A New Player in HIV/neuroAIDS (1 RO1 NS094108)
CELL BIOLOGY & IMMUNOLOGYNINDS: Neurological Disorders & Stroke
2012 Project RN0057: The Role of Reactive Oxygen Species in Intermittent Hypoxia Induced Sympathoexcitation (1R21HL106431-01A1)
INTEGRATIVE PHYSIOLOGYNHLBI: Nat Heart, Lung & Blood Institute
2011 Project G71110: Novel Mechanistic Targets of Steroid Hormones in the Brain (1P01AG027956-01A1)
PHARMACOLOGY & NEUROSCIENCENIA: National Institute on Aging
 
Journals   More...    Close... 
Jouett NP, Moralez G, White DW, Eubank WL, Chen S, Tian J, Zimmerman M, Smith ML, Raven P.. N-Acetyl Cysteine Reduces Hyper-Acute Intermittent Hypoxia Induced Sympathoexcitation in Human Subjects.. Experimental Physiology. 2016 March; 101. (3): 387-396  Published
Chen, S.. A connection between Bayesian and frequentist estimates. Applied Probability and Statistics. 2015 May; 10. (1): 15-19  Published
Cervantes DT, Chen S, Sutor LJ, Stonecipher S, Janoski N, Wright DJ, Busch MP. West Nile virus infection incidence based on donated blood samples and neuroinvasive disease reports, Northern Texas, USA, 2012. Emerging Infectious Diseases. 2015 April; 21. (4): 681-683  Published
Zhang P, Downey HF, Chen S, Shi X.. Two-week Normobaric Intermittent-Hypoxia Exposures Enhance Oxyhemoglobin Equilibrium and Cardiac Responses during Hypoxemia. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology. 2014 September; 307. (6): R721-R730  Published
Zhou Y, Lefante J, Rice J, Chen S.. Using modified approaches on marginal regression analysis of longitudinal data with time-dependent covariates. Statistics in Medicine. 2014 August; 33: 3354–3364  Published
Shi X, Tubb L, Chen S, Fulda KG, Franks S, Reeves R, Lister G.. Associations of health disparities and physical activity with children’s health and academic problems. J. of Exercise Science & Fitness. 2014 June; 12: 7-14  Published
Shi X, Tubb L, Fingers SL, Chen S, Gaffrey J.. Associations of physical activity and dietary behaviors with children’s health and academic problems. Journal of School Health. 2013 January; 83. (1): 1-7  Published
Sun L, Brown R, Chen S, Zhuge Q, Su D‐M.. Aging induced decline in T-lymphopoiesis is primarily dependent on status of progenitor niches in the bone marrow and thymus. Impact Journal on Aging. 2012 September; 4. (9): 606-619  Published
Faramawi MF, Johnson ES, Chen S, Pannala PR.. The incidence of hepatitis E virus infection in the general population of the USA. Epidemiology and Infection. 2011 August; 139. (8): 1145-50  Published
Shande Chen and Xiangrong Shi. Re-parameterization of the Logistic Model in Assessing Changes. Neuroscience & Medicine. 2011 August; 2. (2): 110-116  Published
Chen S. A class of confidence intervals for sequential phase II clinical trials with binary outcome. Journal of Applied Statistics. 2011 March; 38. (3): 479-489  Published
Chen S, Singh KP, Bae S, Bartolucci AA. Associating risk factors with farm injuries using classification tree. Journal of the Indian Society of Agricultural Statistics. 2011 January; 65. (1): 99-103  Published
Moraros J, Bird Y, Chen S, Buckingham R, Meltzer RS, Prapasiri S, Solis LH. The impact of the 2002 Delaware smoking ordinance on heart attack and asthma.. International journal of environmental research and public health. 2010 December; 7. (12): 4169-78  Published
Cervantes DT, Fischbach LA, Goodman KJ, Phillips CV, Chen S, Broussard CS. Exposure to Helicobacter pylori-positive siblings and persistence of Helicobacter pylori infection in early childhood.. Journal of pediatric gastroenterology and nutrition. 2010 May; 50. (5): 481-5  Published
Horsburgh CR Jr, Goldberg S, Bethel J, Chen S, Colson P, Hirsch-Moverman Y, Hughes S, Shrestha-Kuwahara R, Sterling TR, Wall K, Weinfurter P. Latent tuberculosis infection treatment acceptance and completion in the United States and Canada. Chest. 2010; 137. (2): 401-409  Published
Chen S, Laughlin JF. MRI algorithm for medical necessity for auto accident injured patients. Journal of Evaluation in Clinical Practice. 2009. (15): 189-194  Published
Shi X, Schaller FA, Tierney N, Chanthavong P, Chen S, Raven PB and Smith ML. Physically active lifestyle enhances vagal-cardiac function but not central autonomic neural interaction in elderly humans. Exp Biol Med. 2008; 233: 209-218  Published
Gao F, Manatunga AK, Chen S. . Non-parametric estimation for baseline hazards function and covariate effects with time-dependent covariates.. Statistics in medicine. 2007 February 20; 26. (4): 857-68  Published
Chen S. and Manatunga AK. A note on proportional hazards and proportional odds models. Statistics and Probability Letters. 2007; 77. (10): 981-988  Published
Idell S, Allen T, Chen S, Koenig K, Mazar A, and Azghani A. Intrapleural activation, processing, efficacy and duration of protection of single chain Urokinase in EvolvingTetracycline-induced pleural injury in rabbits. Am J Physiol Lung Cell Mol Physiol. 2007; 292: L25-L32  Published
Idell S, Azghani A, Chen S, Koenig K, Mazar A, Kodandapani L, Edeir K, Cines D, Kulikovskaya, I and Allen T. Intrapleural Urokinase, tissue plasminogen activator or single chain Urokinase in tetracycline-induced pleural loculation in rabbits. Exp Lung Res.. 2007; 33: 419-440  Published
Guo Y, Manatunga AK, Chen S, Marcus M. . Modeling menstrual cycle length using a mixture distribution.. Biostatistics (Oxford, England). 2006 January; 7. (1): 100-14  Published
Gao F, Manatunga AK, Chen S. . MSurvPow: a FORTRAN program to calculate the sample size and power for cluster-randomized clinical trials with survival outcomes.. Computer methods and programs in biomedicine. 2005 April; 78. (1): 61-7  Published
Saw A, Smith PA, Sirirungruangsarn Y, Chen S, Hassani S, Harris G, Kuo KN. . Rectus femoris transfer for children with cerebral palsy: long-term outcome.. Journal of pediatric orthopedics. 2003 September - July; 23. (5): 672-8  Published
Coon JS, Marcus E, Gupta-Burt S, Seelig S, Jacobson K, Chen S, Renta V, Fronda G, Preisler HD. . Amplification and overexpression of topoisomerase IIalpha predict response to anthracycline-based therapy in locally advanced breast cancer.. Clinical cancer research : an official journal of the American Association for Cancer Research. 2002 April; 8. (4): 1061-7  Published
Manatunga AK, Chen S. . Sample size estimation for survival outcomes in cluster-randomized studies with small cluster sizes.. Biometrics. 2000 June; 56. (2): 616-21  Published
Richardson D, Chen S. . Data quality assurance and quality control measures in large multicenter stroke trials: the African-American Antiplatelet Stroke Prevention Study experience.; 2. (3): 115-117  Published
Bae S, Ye R, Chen S, Rivers PA, Singh KP. . Risky behaviors and factors associated with suicide attempt in adolescents.. Archives of suicide research : official journal of the International Academy for Suicide Research; 9. (2): 193-202  Published
Zhang P, Downey HF, Chen S, Shi X. Two-week Normobaric Intermittent-Hypoxia Exposures Enhance Oxyhemoglobin Equilibrium and Cardiac Responses during Hypoxemia. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology  Accepted/In-press
 
Books
Chen S, Suzuki S, Podawitz A, and Claassen CA. Trends in rate of suicide by decedent age over time: United States mortality data, 1960-2007. Chan F, Marinova D, Anderssen RS. MODSIM2011, 19th International Congress on Modelling and Simulation. 2011 December: 173-8  Published
 
Faculty Development / Professional Meetings   More...    Close... 
March 19 2009Introduction to Nonparametric Bayesian Analysis
  Role:  Scope: International 
October 25 2008Determine the correlation between comprehensive non smoking ordinances and incidence rates of AMI and asthma
  Role:  Scope: National 
May 12 2008Estimation for Euclidean parameters in semi parametric model
  Role:  Scope: International 
February 6 2007Biostatistics in Clinical Research
 NTXACRP Role:  Scope: National 
January 17 20076th Hawaii International Conference on Statistics, Mathematics and Related Fields
 American Statistical Association-Hawaii Chapter, etc. Role:  Scope: International 
January 16 2006A note on proportional hazards and proportional odds models
 Honolulu, Hawaii Role:  Scope: National/International 
 
Community Engagement
Institutional Service
2012 - Currentthe Faculty Grievance and Appeal Committee, UNTHSC
LocalSchool/Insitutional CommitteesMember
2010 - CurrentIRB
LocalSchool/Insitutional CommitteesMember
Professional Service   More...    Close... 
2014 - CurrentNIH/NIDDK
InternationalJournal/Grant ReviewerGrant Reviewer
2013 - CurrentAnnals of Biometrics & Biostatistics
InternationalEditorial Review Boards/Study SectionsEditorial Board Member
2013 - CurrentThe Scientific World Journal
InternationalEditorial Review Boards/Study SectionsEditorial Board Member
2013 - CurrentJAOA
NationalJournal/Grant ReviewerReviewer
2009 - CurrentJournal of Applied Probability and Statistics
InternationalJournal/Grant ReviewerPeer Reviewer
2009 - CurrentNIH-NIAID
NationalJournal/Grant ReviewerGrant Reviewer
2008 - CurrentBiometrical Journal
InternationalJournal/Grant ReviewerPeer Reviewer
2003 - Currentstatistics in Medicine
NationalJournal/Grant ReviewerReviewer
2010 - 2010Dept of Public Health Sciences, UC Davis
NationalOther Volunteer ActivitiesReviewer
2009 - 2010Journal of Applied Statistics
InternationalJournal/Grant ReviewerPeer Reviewer
Community Service   More...    Close... 
2007 - CurrentAmerican Statistical Association
NationalOther Volunteer ActivitiesMember
2007 - CurrentSPH/Promotion & Tenure Committee
LocalSchool/Insitutional CommitteesMember
2007 - CurrentUNTHSC , Executive Council of Faculty
LocalSchool/Insitutional CommitteesMember
2007 - CurrentSPH Planning & Evaluation Committee, UNTHSC
LocalSchool/Insitutional CommitteesMember
2007 - CurrentInstitute for Cancer Research, UNTHSC
LocalSchool/Insitutional CommitteesMember
2007 - CurrentExecutive Council of the Faculty, UNTHSC
LocalBoard Memberships/Elected Positions
- CurrentSPH/Promotion & Tenure Committee
LocalSchool/Insitutional CommitteesChairman
 
Additional Information
Biographical Sketch


PROFESSIONAL EXPERIENCE

Instructor, Department of Mathematics, Shanghai University of Technology 1982 - 1984

Exchange Visitor, Department of Mathematics, Rochester Institute of Technology 1984 - 1985

Teaching Assistant,Department of Statistics, University of Rochester 1985 - 1988
Research Assistant, Department of Statistics, University of Rochester 1986 - 1987

Statistics Consultant in Computer Center, University of Rochester 1988 - 1989

Research Associate, Division of Biostatistics,University of Rochester 1989 - 1990
Instructor, Division of Biostatistics, University of Rochester 1990 - 1991

Assistant Professor, Department of Biostatistics and associate Scientist in both the Comprehensive Cancer Center and AIDS Center, University of Alabama at Birmingham 1991 - 1995

Assistant Professor, Department of Preventive Medicine, Rush-Presbyterian-St. Luke's Medical Center 1995 - 1999

Associate Professor, Department of Preventive Medicine, Rush-Presbyterian-St. Luke's Medical 2000 - 2001 Center

Associate Professor, Department of Biostatistics, University of North Texas Health Science Center 2001 – 2009

Professor, Department of Biostatistics, University of North Texas Health Science Center 2009 – present

Member, Institute for Cancer Research University of North Texas Health Science Center

Memberships
American Statistical Association
Special Skills
statistical consulting, data management.
 
Last Updated: July 26th 2017